serum klotho levels in trained athletes
نویسندگان
چکیده
conclusions regular aerobic exercise could increase plasma klotho levels, and this could be an explanation for exercise-related anti-aging effects. background klotho is an anti-aging protein that is predominantly secreted by the kidneys. objectives the aim of the study was to measure and compare the circulating klotho levels in the serum of trained athletes and in healthy, non-athlete controls. materials and methods thirty trained football players were enrolled and their serum klotho levels were measured the morning after their last evening exercise training. results the plasma free klotho concentration was significantly higher in the athlete group (3.375 ± 1.48 ng/ml) compared to the non-athletes (1.39 ± 0.43 ng/ml) (p < 0.05). serum levels of cholesterol, triglycerides, calcium, and phosphorus were not significantly different between the two groups.
منابع مشابه
Serum Klotho Levels in Trained Athletes
BACKGROUND Klotho is an anti-aging protein that is predominantly secreted by the kidneys. OBJECTIVES The aim of the study was to measure and compare the circulating Klotho levels in the serum of trained athletes and in healthy, non-athlete controls. MATERIALS AND METHODS Thirty trained football players were enrolled and their serum Klotho levels were measured the morning after their last ev...
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Transmembrane α-Klotho (TM-Klotho), mainly expressed in renal distal tubules, is a co-factor for FGF23 receptor. Circulating soluble α-Klotho (s-Klotho) results from shedding of the ecto-domain of TM-Klotho and has specific effects on urinary Phosphate (P) and Calcium (Ca) transport. The possibility exists that a decrease in TM-Klotho, described in experimental chronic kidney disease (CKD), may...
متن کاملSoluble α-Klotho Serum Levels in Chronic Kidney Disease
Transmembrane α-Klotho (TM-Klotho), expressed in renal tubules, is a cofactor for FGF23-receptor. Circulating soluble-α-Klotho (s-Klotho) results from TM-Klotho shedding and acts on Phosphate (P) and Calcium (Ca) tubular transport. Decreased TM-Klotho, described in experimental chronic kidney disease (CKD), prevents actions of FGF23 and lessens circulating s-Klotho. Thus, levels of s-Klotho cou...
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عنوان ژورنال:
nephro-urology monthlyجلد ۸، شماره ۱، صفحات ۰-۰
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